Season
- Season 0 2012-08-26
- Season 1 2009-07-16
- Season 2 2010-01-14
- Season 3 2010-09-09
- Season 5 2011-09-25
- Season 6 2012-01-08
- Season 7 2012-06-17
- Season 8 2012-09-09
- Season 9 2013-01-06
- Season 10 2013-06-16
- Season 11 2014-01-05
- Season 12 2015-01-04
- Season 13 2016-01-03
- Season 14 2017-01-03
- Season 15 2018-01-07
- Season 16 2019-01-06
- Season 17 2020-01-05
- Season 18 2021-01-03
- Season 19 2022-01-05
- Season 20 2023-01-02
- Season 21 2024-01-07
Episode
- Episode 1: Melissa Gorga & Tabatha Coffey
- Episode 2: Lydia McLaughlin & Kristen Johnston
- Episode 3: Nev Schulman & Kelly Killoren-Bensimon
- Episode 4: Kylie Minogue & Elijah Wood
- Episode 5: Kelly Rowland & Cedric the Entertainer
- Episode 6: Caroline Manzo & Manzo Kids
- Episode 7: Newlyweds: The First Year
- Episode 8: The Real Housewives of OC
- Episode 9: Maggie Gyllenhaal & Martha Stewart
- Episode 10: Cher
- Episode 11: Jeff Lewis
- Episode 12: Lauri Peterson & Mark Feuerstein
- Episode 13: Roble Ali & Alyssa Milano
- Episode 14: Kris Jenner & Pattie Mallette
- Episode 15: Aisha Tyler & Ciara
- Episode 16: Kathy Wakile & Rosie Pierri
- Episode 17: Vicki Gunvalson & Joe Buck
- Episode 18: Giuliana & Bill Rancic
- Episode 19: Patti Stanger
- Episode 20: Wanda Sykes & Susan Lucci
- Episode 21: Jacqueline Laurita & Rebecca Romijn
- Episode 22: Tamra Judge (Barney) & Hoda Kotb
- Episode 23: Jonas Brothers
- Episode 24: TI & Mary Murphy
- Episode 25: Lisa Kudrow & Piper Perabo
- Episode 26: Teresa Giudice & Dr V
- Episode 27: Gretchen Rossi & Billy Eichner
- Episode 28: Debi Mazar & Adam Brody
- Episode 29: Ryan Serhant, Fredrik Eklund & Luis D Ortiz
- Episode 30: Ashanti & Christina Ricci
- Episode 31: Caroline Manzo & Anna Chlumsky
- Episode 32: Alexis Bellino & Jenni Pulos
- Episode 33: Yvette Nicole Brown & Jason Derulo
- Episode 34: Josh Altman, Josh Flagg & Madison Hilderbrand
- Episode 35: Hank Azaria & Taylor Schilling
- Episode 36: Melissa Gorga & Elisabeth Moss
- Episode 37: Joanna Krupa & Lea Black
- Episode 38: Keri Russell & Kyra Sedgwick
- Episode 39: Padma Lakshmi & Tamar Braxton
- Episode 40: Oprah Winfrey
- Episode 41: Danielle Staub
- Episode 42: Adriana De Moura & Ali Larter
- Episode 43: Bethenny Frankel
- Episode 44: Lady Gaga
- Episode 45: Sean Kingston & Gloria Estefan
- Episode 46: Andrew Dice Clay & Kathy Wakile
- Episode 47: Tamra and Eddie Judge
- Episode 48: Nene Leakes & Paula Patton
- Episode 49: The Real World All-Stars: Chris Tamburello, Paula Meronek, Ruthie Alcaide & Danny Roberts
- Episode 50: Jewel & Taye Diggs
- Episode 51: Jacqueline Laurita & Kelly Ripa
- Episode 52: Wendi Mclendon-Covey & Ellen Pompeo
- Episode 53: Nick Carter & Suzanne Somers
- Episode 54: Lucy Liu & Malin Akerman
- Episode 55: Lizzy Caplan & Tony Danza
- Episode 56: One-on-One: Teresa & Joe Giudice
- Episode 57: Alexia Echavarria & Meghan McCain
- Episode 58: Tom Cholicchio & David Arquette
- Episode 59: Jerry O'Connell & Rebel Wilson
- Episode 60: Betsy Brandt & Daniel Radcliffe
- Episode 61: Rosie Pierre & Lance Bass
- Episode 62: Connie Britton & Zachary Quinto
- Episode 63: John Legend & Jason Biggs
- Episode 64: Michael Strahan & Rachel Maddow
- Episode 65: WWHL Wedding Special
- Episode 66: Orlando Bloom & Ian McKellen
- Episode 67: Ja Rule & Lisa Hochstein
- Episode 68: Soleil Moon Frye & Dr Sanjay Gupta
- Episode 69: Carla Hall, Jessica Seinfeld & Rachel Ray
- Episode 70: Cee Lo Green & Lisa Marie Presley
- Episode 71: Bevy Smith, Jenna Jameson & Jennifer Tilley
- Episode 72: Amy Sedaris & Lea Black
- Episode 73: George Takei & Sherri Shepherd
- Episode 74: Josh Altman, Josh Flagg & Madison Hilderbrand
- Episode 75: Johnny Knoxville & Rosie Perez
- Episode 76: Rev. Al Sharpton & Cynthia Bailey
- Episode 77: Marysol Patton & Nancy Grace
- Episode 78: Donnie Wahlberg & Jenny McCarthy
- Episode 79: Christina Hendricks & Dylan McDermott
- Episode 80: Neil Patrick Harris
- Episode 81: Kandi Burruss & Kenya Moore
- Episode 82: Lisa Vanderpump & Whitney Cummings
- Episode 83: Reza Farahan & Zachary Levi
- Episode 84: Giada De Laurent is & Katey Sagal
- Episode 85: The Wanted
- Episode 86: Nelly & Porsha Stewart
- Episode 87: Brandi Glanville & Mark Consuelos
- Episode 88: Mercedes "MJ" Javid & Mike Shouhed
- Episode 89: Gail Simmons & Curtis Stone
- Episode 90: Terrence Howard & Nia Long
- Episode 91: Phaedra Parks, Ben & Jewel Tankard
- Episode 92: Jax Taylor & Stassi Schroeder
- Episode 93: Meredith Vieira & Jesse Tyler Ferguson
- Episode 94: Gina Gershon & Josh Gad
- Episode 95: Angela Bassett & Jennifer Hudson
- Episode 96: Cynthia Bailey & Sandra Bernhard
- Episode 97: Kim Richards & Lisa Whelchel
- Episode 98: Cheyenne Jackson & Lilly Ghalichi
- Episode 99: Patti Stanger
- Episode 100: Whoopi Goldberg & Zoe Saldana
- Episode 101: Fantasia Barrino & Kandi Burruss
- Episode 102: Abigail Breslin & Kyle Richards
- Episode 103: The Cast of Downton Abbey
- Episode 104: Ralph Fiennes & Susan Sarandon
- Episode 105: Sharon Osbourne & Tyler Perry
- Episode 106: Flo Rida & Kenya Moore
- Episode 107: Joyce Giraud De Ohoven & Scheana Marie
- Episode 108: James Marsden, Steve Carrell & Will Ferrell
- Episode 109: Sarah Jessica Parker
- Episode 110: Justin Long & John Leguizamo
- Episode 111: Mariah Carey
Watch What Happens Live with Andy Cohen - Season 10 Episode 68 : Soleil Moon Frye & Dr Sanjay Gupta
Andy Cohen interviews Soleil Moon Frye and Dr Sanjay Gupta.
